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Comparative Analysis of an Integral Component of Bacterial Cell Division from the Lactococcusand BacillusGenera
1Faculty of Biotechnology, Vietnam National University of Agriculture, Hanoi 131000, Vietnam
2Faculty of Agronomy, Vietnam National University of Agriculture, Hanoi 131000, Vietnam
3Department of Biochemistry, National Hospital of Obstetrics and Gynecology, Hanoi 111670, Vietnam
4Faculty of Agricultural Technology, University of Engineering and Technology, Vietnam National University of Hanoi, Hanoi 113100, Vietnam
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Abstract
FtsZ proteins have been well-characterized to play a crucial role in cell division. Unfortunately, data are scarce on FtsZ proteins in the Lactococcus and Bacillus genera. The objective of this study was to analyze the features of FtsZ proteins in the Bacillus and Lactococcus genus groups. By exploring the available genomes, we identified and characterized FtsZ proteins in 19 Bacillus and 22 Lactococcus species. The sizes and weights of the FtsZ proteins ranged from 376 to 410 aa residues and 39.53 to 44.15 kDa in the Bacillus genus, respectively, and from 387 to 430 aa residues and 41.14 to 45.11 kDa in the Lactococcus genus, respectively. All the FtsZ proteins in the Bacillus and Lactococcus species were acidic and globular, and localized in the cytoplasm. Next, 3D modeling and multiple alignments were performed. We realized that the FtsZ proteins in the Bacillus and Lactococcus species exhibited five specific regions. Taken together, our study could provide a general background for further functional characterization of the FtsZ proteins in Bacillus and Lactococcus species.