Current Research, Challenges, and Perspectives of Biotechnology: An Overview

Nguyen Duc Bach 1 and Ly Thi Bich Thuy 2

1Faculty of Biotechnology, Vietnam National University of Agriculture, Hanoi 131000, Vietnam
2Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi 123200, Vietnam
Received: Jan 4, 2019 /
Revised: Jul 13, 2021 /
Published: Jan 5, 2019

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Abstract

Biotechnology is defined as biology-based technology using organisms or their parts to make or modify products or to improve characteristics of plants, animals, and microorganisms for the demands of human beings. Biotechnology profoundly impacts various fields such as agriculture, animal husbandry and veterinary, industry, food science, pharmaceutics and medicine, environment, fine chemistry, biofuels, forensics, and nanotechnology. Nowadays, biotechnology and bioindustries are becoming integral parts of the knowledge-based economy, and therefore, biotechnology has become a powerful and indispensable tool for the development of all countries in the world. As a rule, biotechnology also requires regulatory policies to control genetically modified organisms and derived products to avoid risks to biodiversity, human health, the environment, and ethical issues. This article reviews the current research, challenges, and perspectives of biotechnology as an integration of both life sciences and applied sciences.

Keywords: Animal biotechnology, Plant biotechnology, Environmental biotechnology, Microbial technology, Medicinal biotechnology

Article Details

How to Cite
Bach, N., & Bich Thuy, L. (2019). Current Research, Challenges, and Perspectives of Biotechnology: An Overview. Vietnam Journal of Agricultural Sciences, 1(2), 187-199. https://doi.org/10.31817/vjas.2018.1.2.09

References

    Adrio J. L. and Demain A. L. (2014). Microbial enzymes: tools for biotechnological processes. Biomolecules. Vol 4 (1). pp. 117-139.
    Alexandrov T. Chernyavsky I., Becker M., Eggeling F. V. and Nikolenko S. (2013). Analysis and interpretation of imaging mass spectrometry data by clustering mass-to-charge images according to their spatial similarity. Analytical Chemistry. Vol 85 (23). pp. 11189-11195.
    Asma U.l. Husna., Awan M. A., Mehmood A., Sultana T., Shahzad Q., Ansari M. S., Rakha B. A., Saqlan Naqvi S. M. and Akhter S. (2017). Sperm sexing in Nili-Ravi buffalo through modified swim up: Validation using SYBR® green real-time PCR. Animal Reproduction Science. Vol 182. pp. 69-76.

    Asturiano J. F., Cabrita E. and Horvath A. (2017). Progress, challenges and perspectives on fish gamete cryopreservation: A mini-review. General Comparative Endocrinology. Vol 245. pp. 69-76.
    Atanassova A. and Keiper F. (2018). Plant breeding innovation: A global regulatory perspective. Cereal Chemistry. Vol 95 (1). pp. 8-16.

    Bagri D. S., Upadhyay D. C., Jain S. K. and Upadhyay C. P. (2018). Biotechnological improvement of nutritional and therapeutic value of cultivated potato. Frontiers in Bioscience (Scholar Edition). Vol 10. pp. 217-228.
    Bai Y., Sartor M. and Cavalcoli J. (2012). Current status and future perspectives for sequencing livestock genomes. Journal of Animal Science Biotechnology. Vol 3 (1). Article 8.
    Bawa A. S. and Anilakumar K. R. (2013). Genetically modified foods: safety, risks and public concerns-a review. Journal of Food Science and Technology. Vol 50 (6). pp. 1035-1046.
    Baweja M., Nain L., Kawarabayasi Y. and Shukla P. (2016). Current Technological Improvements in Enzymes toward Their Biotechnological Applications. Frontiers in Microbiology. Vol 7 (965). Article 965, 13 pages. doi: 10.3389/fmicb.2016.00965.
    Bhat S. A., Malik A. A., Ahmad S. M., Shah R. A., Ganai N. A., Shafi S. S. and Shabir N. (2017). Advances in genome editing for improved animal breeding: A review. Veterinary World. Vol 10 (11). pp. 1361-1366.
    Bosze Z. and Hiripi L. (2012). Recombinant protein expression in milk of livestock species. Methods Mol Biol. Vol 824. pp. 629-641.
    Carter H., Hofree M. and Ideker T. (2013). Genotype to phenotype via network analysis. Current Opinion in Genetics & Development. Vol 23 (6). pp. 611-621.
    Chandler D., Bailey A. S., Tatchell G. M., Davidson G., Greaves J. and Grant W. P. (2011). The development, regulation and use of biopesticides for integrated pest management. Philosophical transactions of the Royal Society of London. Series B, Biological Sciences. Vol 366 (1573). pp. 1987-1998.
    Chapman J., Ismail A. E. and Dinu C. Z. (2018). Industrial Applications of Enzymes: Recent Advances, Techniques, and Outlooks. Catalysts 2018. Vol 8 (6). Article 238, 26 pages. doi:10.3390/catal8060238.
    Chekol C. and Gebreyohannes M. (2018). Application and Current Trends of Biotechnology: a Brief Review. Austin Journal of Biotechnology & Bioengineering. Vol 5 (1). pp. 1-8.
    Coelho A. C. and Garcia Diez J. (2015). Biological Risks and Laboratory-Acquired Infections: A Reality That Cannot be Ignored in Health Biotechnology. Frontiers in Bioengineering and Biotechnology. Vol 3 (56). Article 56.
    Das N. and Chandran P. (2011). Microbial degradation of petroleum hydrocarbon contaminants: an overview. Biotechnology Research International. Vol 2011 (10). Article 941810, 13 pages.
    Den W., Sharma V. K., Lee M, Nadadur G. and Varma R. S. (2018). Lignocellulosic Biomass Transformations via Greener Oxidative Pretreatment Processes: Access to Energy and Value-Added Chemicals. Frontiers in Chemistry. Vol 6 (141). Article 141. doi: 10.3389/fchem.2018.00141.
    Devuyst O. (2015). The 1000 Genomes Project: Welcome to a New World. Peritoneal Dialysis International. Vol 35 (7). pp. 676-677.
    Dua M., Singh A., Sethunathan N. and Johri A. K. (2002). Biotechnology and bioremediation: successes and limitations. Applied Microbiology and Biotechnology. Vol 59. pp. 143-152.
    Dubock A. (2017). An overview of agriculture, nutrition and fortification, supplementation and biofortification: Golden Rice as an example for enhancing micronutrient intake. Agriculture & Food Security. Vol 6. Article 59, 20 pages. doi: 10.1186/s40066-017-0135-3.
    Dunisławska A., Łachmańska J., Slawinska A. and Siwek M. (2017). Next generation sequencing in animal science - A review. Animal Science Papers and Reports. Vol 35 (3). pp. 205-224.
    Espinosa-Cervantes R. and Cordova-Izquierdo A. (2013). Sexing sperm of domestic animals. Tropical Animal Health and Production. Vol 45 (1). pp. 1-8.
    Fleming D., Musser F., Reisig D., Greene J., Taylor S., Parajulee M., Lorenz G., Catchot A., Gore J., Kerns D., Stewart S., Boykin D., Caprio M. and Little N. (2018). Effects of transgenic Bacillus thuringiensis cotton on insecticide use, heliothine counts, plant damage, and cotton yield: A meta-analysis, 1996-2015. PLoS One. Vol 13 (7). Article e0200131. doi: 10.1371/journal.pone.0200131.
    Glazer A. N. and Nikaido H. (1995). Microbial biotechnology: fundamentals of applied microbiology. Freeman, New York.
    Gopalakrishnan S., Sathya A., Vijayabharathi R., Varshney R. K., Gowda C. L. L. and Krishnamurthy L. (2015). Plant growth promoting rhizobia: challenges and opportunities. Biotech. Vol 5 (4). pp. 355-377.
    Gurung N., Ray S., Bose S. and Rai V. (2013). A broader view: microbial enzymes and their relevance in industries, medicine, and beyond. Biomed Research International. Vol 2013 (10). Article 329121, 18 pages.
    Hefferon K. L. (2015). Nutritionally enhanced food crops; progress and perspectives. International Journal of Molecular Sciences. Vol 16 (2). pp. 3895-3914.
    Hryhorowicz M., Zeyland J., Słomski R. and Lipiński D (2017). Genetically Modified Pigs as Organ Donors for Xenotransplantation. Molecular Biotechnology. Vol 59 (9-10). pp. 435-444.
    Jayne T. S., Minde I. J. and Argwings-Kodhek G. (2002). Perspectives on Agricultural Transformation: A View from Africa. Nova Science Publisher, New York. pp. 119.
    Ju X. D., Xu J. and Sun Z. S. (2018). CRISPR Editing in Biological and Biomedical Investigation. Journal of Cellular Biochemistry. Vol 119 (1). pp. 52-61.
    Jungbauer A., Scheper T. and Pühler A. (2012), Current research and future perspectives of applied biotechnology. Journal of Biotechnology. Vol 162 (4). Article 355. doi: 10.1016/j.jbiotec.2012.11.004.
    Kamthan A., Chaudhuri A., Kamthan M. and Datta A. (2016). Genetically modified (GM) crops: milestones and new advances in crop improvement. Theor Appl Genet, 2016. Vol 129 (9). pp. 1639-1655.
    Karigar C. S. and Rao S. S. (2011). Role of microbial enzymes in the bioremediation of pollutants: a review. Enzyme Res, 2011. Vol 2011 (10). Article 805187, 11 pages.
    Kilbane J. J. II (2016). Future Applications of Biotechnology to the Energy Industry. Frontiers in Microbiology. Vol 7 (86). Article 86. doi: 10.3389/fmicb.2016.00086.
    Kim E. Y., Park M. J., Park H. Y., Noh E. J., Noh E. H, Park K. S., Lee J. B., Jeong C. J., Riu K. Z. and Park S. P. (2012). Improved cloning efficiency and developmental potential in bovine somatic cell nuclear transfer with the oosight imaging system. Cell Reprogram. Vol 14 (4). pp. 305-311.
    Klee H. J. (2010). Improving the flavor of fresh fruits: genomics, biochemistry, and biotechnology. New Phytologist. Vol 187 (1). pp. 44-56.
    Kutyna D. R. and Borneman A. R. (2018). Heterologous Production of Flavour and Aroma Compounds in Saccharomyces cerevisiae. Genes (Basel). Vol 9 (7). doi: 10.3390/genes9070326.
    Leuchtenberger W., Huthmacher K. and Drauz K. (2005). Biotechnological production of amino acids and derivatives: current status and prospects. Applied Microbiology and Biotechnology. Vol 69 (1). pp. 1-8.
    Li Y., Zhang G. and Pfeifer B. A. (2015). Current and emerging options for taxol production. Advances in Biochemical Engineering/Biotechnology. Vol 148. pp. 405-425.
    Li S., Yang X., Yang S., Zhu M. and Wang X. (2012). Technology prospecting on enzymes: application, marketing and engineering. Computational and Structural Biotechnology Journal. Vol 2 (2): e201209017.
    Maghari B. M. and Ardekani A. M. (2011). Genetically modified foods and social concerns. Avicenna Journal of Medical Biotechnology. Vol 3 (3). pp. 109-117.
    Maksimenko O. G., Deykin A. V., Khodarovich Y. M. and Georgiev P. G. (2013). Use of transgenic animals in biotechnology: prospects and problems. Acta Naturae, 2013. Vol 5 (1). pp. 33-46.
    Mammadov J., Aggarwal R., Buyyarapu R. and Kumpatla S. (2012). SNP Markers and Their Impact on Plant Breeding. International Journal of Plant Genomics. Vol 2012. pp. 1-11.
    Maryam B. M., Datsugwai M. S. S. and Shehu I. (2017a). The Role of Biotechnology in Food Production and Processing. Engineering and Applied Sciences. Vol 2 (6). pp. 113-124.
    Maryam D. M., Datsugwai M. S. S. and Shehu I. (2017b). The Role of Biotechnology in Food Production and Processing. Industrial Engineering. Vol 1 (1). pp. 24-35.
    Matassa S., Boon N., Pikaar I. and Verstraete W. (2016). Microbial protein: future sustainable food supply route with low environmental footprint. Microbial Biotechnology. Vol 9 (5). pp. 568-575.
    McCullers J. A. and Dunn J. D. (2008). Advances in vaccine technology and their impact on managed care. Pharmacy and Therapeutics, 2008. Vol 33 (1). pp. 35-41.
    Mohamad N. R., Marzuki N. H. C., Buang N. A., Huyop F. and Wahab R. A. (2015). An overview of technologies for immobilization of enzymes and surface analysis techniques for immobilized enzymes. Biotechnology, Biotechnological Equipment. Vol 29 (2). pp. 205-220.
    Moshelion M. and Altman A. (2015). Current challenges and future perspectives of plant and agricultural biotechnology. Trends in Biotechnology. Vol 33 (6). pp. 337-342.
    Murray J. D. and Maga E. A. (2016). Genetically engineered livestock for agriculture: a generation after the first transgenic animal research conference. Transgenic Research. Vol 25 (3). pp. 321-327.
    Nabavizadeh S. L., Mehrabani D., Vahedi Z. and Manafi F. (2016). Cloning: A Review on Bioethics, Legal, Jurisprudence and Regenerative Issues in Iran. World Journal of Plastic Surgery. Vol 5 (3). pp. 213-225.
    Nascimento I. P. and Leite L. C. (2012). Recombinant vaccines and the development of new vaccine strategies. Brazilian Journal of Medical and Biological Research. Vol 45 (12). pp. 1102-1111.
    Nguyen V. T., Kwon Y. S. and Gu M. B. (2017). Aptamer-based environmental biosensors for small molecule contaminants. Current Opinion in Biotechnology. Vol 45. pp. 15-23.
    Nzila A., Razzak S. A. and Zhu J. (2016). Bioaugmentation: An Emerging Strategy of Industrial Wastewater Treatment for Reuse and Discharge. International Journal of Environmental Research and Public Health. Vol 13 (9). doi: 10.3390/ijerph13090846.
    Ogata T., Iwashita Y., and Kawada T. (2017)., Construction of a brewing yeast expressing the glucoamylase gene STA1 by mating. Journal of The Institute of Brewing. Vol 123 (1). pp. 66-69.
    Ohashi H., Hasegawa M., Wakimoto K. and Miyamoto-Sato E. (2015). Next-generation technologies for multiomics approaches including interactome sequencing. Biomed Research International. Vol 2015 (10). Article 104209, 9 pages.
    Omole I. A. (2017). Biotechnology as an Important Tool for Improving Fish Productivity. American Journal of Bioscience and Bioengineering. Vol 5 (1). pp. 17-22.
    Perez-de-Castro A. M., Vilanova S., Canizares J., Pascual L., Blanca J. M., Diez M. J., Prohens J. and Pico B. (2012). Application of genomic tools in plant breeding. Current Genomics. Vol 13 (3). pp. 179-195.
    Popa V. I. (2018). Biomass for Fuels and Biomaterials. Biomass as Renewable Raw Material to Obtain Bioproducts of High-Tech Value. Vol 2018. pp. 1-37.
    Ramana K. V., Xavier J. R. and Sharma R. K. (2017). Recent Trends in Pharmaceutical Biotechnology. Pharmaceutical Biotechnology: Current Research. Vol 1 (5). pp. 1-10.
    Singh R. P., Signh P. K., Gupta R. and Singh R. L. (2018). Chapter 2 - Biotechnological Tools to Enhance Sustainable Production. In: Signh R. L. and Mondal S. (Ed.), Biotechnology for Sustainable Agriculture, Emerging Approaches and Strategies. pp. 19-66. doi: 10.1016/B978-0-12-812160-3.00002-7.
    Singh H. B., Jha A. and Keswani C. (2016a). Intellectual Property Issues in Biotechnology. In: Singh H. B., Jha A. and Keswani C. (Ed.), Biotechnology in Agriculture, Medicine and Industry: An Overview. CAB International 2016, Wallingford.). pp. 1-4.
    Singh R., Kumar M., Mittal A. and Mehta P. K. (2016b). Microbial enzymes: industrial progress in 21st century. Biotech. Vol 6 (2). Article 174. doi: 10.1007/s13205-016-0485-8.
    Singh J. S. and Strong P. J. (2016). Biologically derived fertilizer: A multifaceted bio-tool in methane mitigation. Ecotoxicology and Environmental Safety. Vol 124. pp. 267-276.
    Škrbić Z. (2018). Biotechnology in animal husbandary. Journal for the Improvement of Animal Husbandry. Vol 34 (2). pp. 127-267.
    Tang W. L. and Zhao H. (2009). Industrial biotechnology: Tools and applications. Biotechnology Journal. Vol 4. pp. 1725-1739.
    Ufaz S. and Galili G. (2008). Improving the content of essential amino acids in crop plants: goals and opportunities. Plant Physiology. Vol 147 (3). pp. 954-961.
    Vujic G., Gonzalez-Roof A., Stanisavljević N. and Ragossnig A. M. (2015). Municipal solid waste development phases: Evidence from EU27. Waste Management & Research. Vol 33 (12). pp. 1112-1120.
    Yadav A. K., Tomar S. S., Jha A. K. and Signh J. (2017). Importance of Molecular Markers in Livestock Improvement: A Review. International Journal of Agriculture Innovations and Research. Vol 5 (4). ISSN (online) 2319-1473, 8 pages.
    Yang W., Kang X., Yang Q., Lin Y. and Fang M. (2013). Review on the development of genotyping methods for assessing farm animal diversity. Journal of Animal Science and Biotechnology. Vol 4 (1). Article 2. doi: 10.1186/2049-1891-4-2.
    Wheeler M. B. (2013). Transgenic Animals in Agriculture. Nature Education Knowledge. Vol 4 (11). Article 1.